Pride can be a major stumbling block. Pride develops as we begin to have a high opinion of ourselves.
Proverbs 16:5 The LORD detests all the proud of heart.
Proverbs 16:18 Pride goes before destruction, a haughty spirit before a fall.
Arrogance can also be seen as pride. When we are no longer humble and feel that we have everything in place and it is just that everyone else is missing it, we stand at a dangerous place.
Pride is one of the major attitudes of the heart that is a stumbling block to going for God. It is as we are humble that God shows Himself to us.
Psalm 18:27 You deliver the humble but condemn the proud and haughty ones. James 4:6 God gives strength to the humble but sets himself against the proud and haughty.